top of page

Last 5 years published articles & reviews

1200px-US-NLM-PubMed-Logo.svg.png
Google_Scholar_logo_2015.PNG
A4_2_current_01_edited.jpg

Publications

2024

​

  • B Lekbaby, J Vaquero, A Pavy, M Minini, E Gonzalez-Sanchez, J Augustin, L Fouassier. Experimental model of biliary tract cancers : subcutaneous xenograft of human cell lines in immunodeficient nude mouse. Methods in Cell Biology 2024. In: Kroemer, G., Pol, J., Martins, I. (eds) Liver Carcinogenesis. Methods in Molecular Biology, vol 2769. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-3694-7_7

2023

  • V Bou Malham, N Benzoubir, J Vaquero, C Desterke,J Agnetti, P Xuan Song, E Gonzalez-Sanchez, A Arbelaiz, S Jacques, E Di Valentin, S Rahmouni, T Zea Tan, D Samuel, JP Thiery, M Sebagh, L Fouassier, A Gassama-Diagne. Intrinsic cancer cell Phosphoinositide 3-kinase δ regulates fibrosis and vascular development in cholangiocarcinoma. Liver International 2023. https://doi.org/10.1111/liv.15751
     

  • M Minini & L Fouassier. Cancer-associated fibroblasts and extracellular matrix: Therapeutical Strategies for Modulating the Cholangiocarcinoma Microenvironment. Current Oncology 2023. https://doi.org/10.3390/curroncol30040319

​

  • DF Calvisi, L Boulter, J Vaquero, A Saborowski, L Fabris, P Rodrigues, C Coulouarn, R Castro, O Segatto, C Raggi, L van der Laan, G Carpino, B Goeppert, S Roessler, T Kendall, M Evert, E Gonzalez-Sanchez, J Valle, A Vogel, J Bridgewater, M Borad, G Gores, L Roberts, J Marin, J Andersen, D Alvaro, A Forner, J Banales, V Cardinale, R Macias, S Vicent, X Chen, C Braconi, M Verstegen, and L Fouassier. Criteria for preclinical models of cholangiocarcinoma: scientific and medical relevance.  Nat Rev Gastroenterol Hepatol 2023. https://doi.org/10.1038/s41575-022-00739-y 

2022

  • H Decauchy, A Pavy, M Camus, L Fouassier*, T Dufour*. * co-leadership. Cold plasma endoscopy applied to biliary ducts: feasibility risk assessment on human-like and porcine models for the treatment of cholangiocarcinoma. Journal of Physics D: Applied Physics 2022. https://doi.org/10.1088/1361-6463/ac8c4d

​

  • Duwe L, Fouassier L, Lafuente-Barquero, J, Andersen JB. Unraveling the actin cytoskeleton in the malignant transformation of cholangiocyte biology. Transl Oncol. 2022. 13;26:101531. https://doi.org/10.1016/j.tranon.2022.101531 

​

  • J Vaquero, A Pavy, E Gonzalez-Sanchez, M Meredith, A Arbelaiz, L Fouassier. Genetic alterations shaping tumor response to anti-EGFR therapies. Drug Resistance Update 2022. 64:100863. https://doi.org/10.1016/j.drup.2022.100863

2021

  • J Paillet, C Plantureux, S Lévesque, J Le Naour, G Stoll, A Sauvat, P Caudana, J Tosello Boari, N Bloy, I Martins, P Opolon, A Checcoli, A Delaune, P de la Grange, J Hamroune, F Letourneur, G Autret, P S.C. Leung, M. E Gershwin, J S. Zhu, M J. Kurth, B Lekbaby, J Augustin, Y Kim, S Gujar, C Coulouarn, L Fouassier, L Zitvogel, E Piaggio, C Housset, P Soussan, M. C Maiuri, G Kroemer, J G. Pol. Autoimmunity affecting the biliary tract fuels the immunosurveillance of cholangiocarcinoma. J Exp Med 2021 ; 218(10):e20200853. https://doi.org/10.1084/jem.20200853

​

  • A Nicolas-Boluda, J Vaquero, S Barrin, C Kantari-Mimoun, M Ponzo, G Renault, P Deptuła, K Pogoda, R Bucki, I Cascone, J Courty, L Fouassier, F Gazeau, E Donnadieu. Tumor stiffening reversion through collagen crosslinking inhibition improves T cell migration and anti-PD-1 treatment. (preprint:bioRxiv 2020.05.19.104430). eLife 2021 10:e58688. https://doi.org/10.7554/eLife.58688

​

  • C Lobe, M Vallette, A Arbelaiz, E Gonzalez-Sanchez, L Izquierdo, A Pellat, N Guedj, C Louis, V Paradis, J M Banales, C Coulouarn, C Housset, J Vaquero, L Fouassier. ZEB1 promotes cholangiocarcinoma progression through tumour dedifferentiation and tumour-stroma paracrine signaling. Hepatology 2021; 74(6):3194-3212. https://doi.org/10.1002/hep.32069

​

  • Gonzalez-Sanchez E, El Mourabit H, Jager M, Clavel M, Moog S, Vaquero J, Ledent T, Cadoret A, Gautheron J, Fouassier L, Wendum D, Chignard N, Housset C. Cholangiopathy aggravation is caused by VDR ablation and alleviated by VDR-independent vitamin D signaling in ABCB4 knockout mice. Biochim Biophys Acta Mol Basis Dis. 2021; 1867(4):166067. https://doi.org/10.1016/j.bbadis.2020.166067

​

  • M Cadamuro, A LasagnI, A Lamarca, L Fouassier, M Guido, E Gringeri, U Cillo, M Strazzabosco, JC Marin, JM Banales, L Fabris. Targeted therapies for extrahepatic cholangiocarcinoma: preclinical and clinical development and prospects for the clinic. Expert Opinion on Investigational Drugs 2021;30(4):377-388. https://doi.org/10.1080/13543784.2021.1880564

​

2020

  • A Nicolás-Boluda, Z Yang, T Guilbert, L Fouassier, F Carn, F Gazeau, MP Pileni. Self-assemblies of Fe3O4 nanocrystals: Towards nanoscale precision of photothermal effects in the tumor microenvironment. Advanced Functional Materials 2020;21(4) 2006824. https://doi.org/10.1002/adfm.202006824

​

  • J Vaquero, F Judée, M Vallette, H Decauchy, A Arbelaiz, L Aoudjehane, O Scatton, E Gonzalez-Sanchez, F Merabtene, J Augustin, C Housset, T Dufour, Fouassier L. Cold-atmospheric plasma induces tumor cell death in preclinical in vivo and in vitro models of human cholangiocarcinoma. Cancers 2020; 12(5): E1280. https://doi.org/10.3390/cancers12051280

​

  • Nicolás-Boluda A, Vaquero J, Laurent G, Renault G, Bazzi R, Donnadieu E, Roux S, Fouassier L*, F Gazeau*. * co-leadership. Targeting cancer-associated fibroblasts by gold decorated iron oxide nanoflowers for photothermal therapy of desmoplastic cholangiocarcinoma. ACS NANO 2020; 14(5):5738-5753. https://doi.org/10.1021/acsnano.0c00417

​

​

  • Banales J, Marin JJ, Lamarca A, Rodrigues P, Khan S, Roberts L, Cardinale V, Carpino G, Andersen J, Braconi C, Calvisi D, Perugorria M, Fabris L, Boulter L, Macias R, Gaudio E, Alvaro D, Gradilone S, Strazzabosco M, Marzioni M, Coulouarn C, Fouassier L, Raggi C, Invernizzi P, Mertens JC, Moncsek A, Rizvi S, Heimbach J, Koerkamp B, Bruix J, Forner A, Bridgewater J, Valle J, and Gores G. Cholangiocarcinoma 2020: next Horizon. Nat Rev Gastroenterol Hepatol 2020; 17:557-588. https://doi.org/10.1038/s41575-020-0310-z

​

2019

  • Majdi A, Aoudjehane L, Ratziu V, Islam T, Afonso M, Conti F, Mestiri T, Lagouge M, Foufelle F, Ballenghien F, Ledent T, Moldes M, Cadoret A, Fouassier L, Delaunay JL, Aït-Slimane T, Courtois G, Fève B, Scatton O, Prip-Buus C, Rodrigues CMP, Housset C, Gautheron J. Inhibition of receptor-interacting protein kinase 1 improves experimental non-alcoholic fatty liver disease. J Hepatol 2019; 72(4):627-635. https://doi.org/10.1016/j.jhep.2019.11.008

​

  • Bénabou E, Salamé Z, Wendum D, Lequoy M, Tahraoui S, Merabtene F, Chrétien Y, Scatton O, Rosmorduc O, Fouassier L, Fartoux L, Praz F, Desbois-Mouthon C. Insulin receptor isoform A regulates tumor progression in human hepatocellular carcinoma. Cancer Letters 2019; 450:155-168. https://doi.org/10.1016/j.canlet.2019.02.037

​

  • Judée F, Vaquero J, Guégan S, Fouassier L*, Dufour T*. * co-leadership. Atmospheric pressure plasma jets applied to cancerology: correlating electrical configuration with in vivo toxicity and therapeutic efficiency. Journal of Physics D: Applied Physics 2019; 52:245201. https://doi.org/10.1088/1361-6463/ab0fbb

​

  • L Fouassier, M Marzioni, M B. Afonso, S Dooley, K Gaston, G Giannelli, C M. P. Rodrigues, E Lozano, S Mancarella, O Segatto, J Vaquero, JJ. G. Marin, C Coulouarn. Signaling networks in cholangiocarcinoma: molecular pathogenesis, targeted therapies and drug resistance. Liver International 2019; 28 Suppl 1:43-62. https://doi.org/10.1111/liv.14102

2018

  • Vaquero J, Lobe C, Tahraoui S, Clapéron A, Mergey M, Merabtene F, Wendum D, Housset C, Coulouarn C, Desbois-Mouthon C, Praz F, Fouassier L. IGF2/IR/IGF1R pathway in tumor cells and myofibroblasts mediates resistance to EGFR inhibition in cholangiocarcinoma. Clin Cancer Res 2018 ;17:4282-4296. https://doi.org/10.1158/1078-0432.CCR-17-3725

​

​

bottom of page